4OO8
Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA
Summary for 4OO8
Entry DOI | 10.2210/pdb4oo8/pdb |
Descriptor | CRISPR-associated endonuclease Cas9/Csn1, RNA (97-MER), DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3'), ... (4 entities in total) |
Functional Keywords | hydrolase-dna-rna complex, hydrolase/dna/rna |
Biological source | Streptococcus pyogenes serotype M1 |
Total number of polymer chains | 6 |
Total formula weight | 395168.71 |
Authors | Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2014-01-31, release date: 2014-02-26, Last modification date: 2024-04-03) |
Primary citation | Nishimasu, H.,Ran, F.A.,Hsu, P.D.,Konermann, S.,Shehata, S.I.,Dohmae, N.,Ishitani, R.,Zhang, F.,Nureki, O. Crystal structure of Cas9 in complex with guide RNA and target DNA Cell(Cambridge,Mass.), 156:935-949, 2014 Cited by PubMed: 24529477DOI: 10.1016/j.cell.2014.02.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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