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4ONG

Fab fragment of 3D6 in complex with amyloid beta 1-40

Summary for 4ONG
Entry DOI10.2210/pdb4ong/pdb
Related4ONF
Descriptor3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ... (7 entities in total)
Functional Keywordsantibody, amyloid beta peptide, immune system
Biological sourceMus musculus (mouse)
More
Cellular locationMembrane; Single-pass type I membrane protein: P05067
Total number of polymer chains3
Total formula weight54789.84
Authors
Feinberg, H.,Saldanha, J.W.,Diep, L.,Goel, A.,Widom, A.,Veldman, G.M.,Weis, W.I.,Schenk, D.,Basi, G.S. (deposition date: 2014-01-28, release date: 2014-06-11, Last modification date: 2017-11-22)
Primary citationFeinberg, H.,Saldanha, J.W.,Diep, L.,Goel, A.,Widom, A.,Veldman, G.M.,Weis, W.I.,Schenk, D.,Basi, G.S.
Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.
Alzheimers Res Ther, 6:31-31, 2014
Cited by
PubMed: 25024748
DOI: 10.1186/alzrt261
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

数据于2024-03-27公开中

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