4OLF

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP

4OLF の概要

• エントリーDOI: 10.2210/pdb4olf/pdb
• 関連するPDBエントリー: 4NCX
• 分子名称: Proline--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... (7 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, prolyl-trna synthetase, ligase
• 由来する生物種: Plasmodium falciparum
• 細胞内の位置: Cytoplasm : Q8I5R7
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61433.38

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2014-01-23, 公開日: 2015-04-15, 最終更新日: 2023-09-20)

• 主引用文献: Dranow, D.M.,Edwards, T.E.,Lorimer, D.,Seattle Structural Genomics Center for Infectious Disease; Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP; To be Published,

実験手法

X-RAY DIFFRACTION (2.9 Å)