4OKN
Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate
Summary for 4OKN
Entry DOI | 10.2210/pdb4okn/pdb |
Related | 4OJN |
Descriptor | L-lactate dehydrogenase A chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXALATE ION, ... (6 entities in total) |
Functional Keywords | rossmann fold, nadh/nad+ cofactor, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00338 |
Total number of polymer chains | 8 |
Total formula weight | 306170.06 |
Authors | Kolappan, S.,Craig, L. (deposition date: 2014-01-22, release date: 2014-12-03, Last modification date: 2024-02-28) |
Primary citation | Kolappan, S.,Shen, D.L.,Mosi, R.,Sun, J.,McEachern, E.J.,Vocadlo, D.J.,Craig, L. Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71:185-195, 2015 Cited by PubMed: 25664730DOI: 10.1107/S1399004714024791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)