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4O6L

Crystal Structure of TTK kinase domain with an inhibitor: 401498 (N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide)

Summary for 4O6L
Entry DOI10.2210/pdb4o6l/pdb
DescriptorDual specificity protein kinase TTK, N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide, GLYCEROL, ... (4 entities in total)
Functional Keywordskinase, ttk, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight66588.73
Authors
Qiu, W.,Plotnikova, O.,Feher, M.,Awrey, D.E.,Chirgadze, N.Y. (deposition date: 2013-12-22, release date: 2014-12-24)
Primary citationQiu, W.,Plotnikova, O.,Feher, M.,Awrey, D.E.,Chirgadze, N.Y.
Crystal Structure of TTK kinase domain with an inhibitor: 401498
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

227111

건을2024-11-06부터공개중

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