4O6L
Crystal Structure of TTK kinase domain with an inhibitor: 401498 (N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Dual specificity protein kinase TTK | polymer | 281 | 32699.2 | 2 | UniProt (P33981) Pfam (PF00069) In PDB | Homo sapiens (human) | Phosphotyrosine picked threonine-protein kinase, PYT |
2 | A, B | N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide | non-polymer | 503.0 | 2 | Chemie (2QK) | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65398.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1190.3 | |
All* | Total formula weight | 66588.7 |