4O58

Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin

4O58 の概要

• エントリーDOI: 10.2210/pdb4o58/pdb
• 分子名称: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, Fab F045-092 light chain, ... (10 entities in total)
• 機能のキーワード: immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Influenza A virus; 詳細
• 細胞内の位置: Virion membrane ; Single-pass type I membrane protein : P03435 P03435
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 107891.14

構造登録者

Lee, P.S.,Wilson, I.A. (登録日: 2013-12-19, 公開日: 2014-04-16, 最終更新日: 2023-09-20)

• 主引用文献: Lee, P.S.,Ohshima, N.,Stanfield, R.L.,Yu, W.,Iba, Y.,Okuno, Y.,Kurosawa, Y.,Wilson, I.A.; Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.; Nat Commun, 5:3614-3614, 2014; PubMed: 24717798; DOI: 10.1038/ncomms4614

実験手法

X-RAY DIFFRACTION (2.7501 Å)