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4O56

Structure of PLK1 in complex with peptide

Summary for 4O56
Entry DOI10.2210/pdb4o56/pdb
DescriptorSerine/threonine-protein kinase PLK1, synthetic peptide, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordsplk1 polo box domain, polo box domain, kinase domain, transferase-peptide complex, transferase/peptide
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P53350
Total number of polymer chains2
Total formula weight29108.71
Authors
Wang, T. (deposition date: 2013-12-19, release date: 2014-12-24, Last modification date: 2023-11-08)
Primary citationQuan, J.M.,Wang, T.,Shan, H.M.
Integration of Charge-dipole Interaction and Intramolecular Hydrogen Bond in Ligand Design for the Polo-Box Domain of Polo-like Kinase 1
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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