4O3X

Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Phe-171-Ala from Actinobacillus pleuropneumoniae H49

4O3X の概要

• エントリーDOI: 10.2210/pdb4o3x/pdb
• 関連するPDBエントリー: 4O3W 4O3Y 4O3Z 4O49 4O4U 4O4X
• 分子名称: Transferrin binding protein B (2 entities in total)
• 機能のキーワード: structure-based vaccine design, transferrin receptor, iron acquisition, host pathogen interaction, surface lipoprotein, metal transport
• 由来する生物種: Actinobacillus pleuropneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28025.89

構造登録者

Calmettes, C.,Yu, R.H.,Schryvers, A.B.,Moraes, T.F. (登録日: 2013-12-18, 公開日: 2015-01-14, 最終更新日: 2024-02-28)

• 主引用文献: Frandoloso, R.,Martinez-Martinez, S.,Calmettes, C.,Fegan, J.,Costa, E.,Curran, D.,Yu, R.H.,Gutierrez-Martin, C.B.,Rodriguez-Ferri, E.F.,Moraes, T.F.,Schryvers, A.B.; Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities.; Infect.Immun., 83:1030-1038, 2015; PubMed: 25547790; DOI: 10.1128/IAI.02572-14

実験手法

X-RAY DIFFRACTION (2.5 Å)