4O1M

Toxoplasma gondii Enoyl acyl carrier protein reductase

4O1M の概要

• エントリーDOI: 10.2210/pdb4o1m/pdb
• 関連するPDBエントリー: 2O2S 2O2Y 2O50 2PTG 3NJ8
• 分子名称: Enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: rossmann fold, oxidoreductase, enoyl acyl carrier protein reductase
• 由来する生物種: Toxoplasma gondii
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 204329.88

構造登録者

Muench, S.P.,Wilkinson, C.,Prigge, S.T.,Rice, D.W. (登録日: 2013-12-16, 公開日: 2014-02-05, 最終更新日: 2024-04-03)

• 主引用文献: Wilkinson, C.,Mcphillie, M.J.,Zhou, Y.,Woods, S.,Afanador, G.A.,Rawson, S.,Khaliq, F.,Prigge, S.T.,Roberts, C.W.,Rice, D.W.,Mcleod, R.,Fishwick, C.W.,Muench, S.P.; The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target; Bioorg.Med.Chem.Lett., 24:911-916, 2014; PubMed: 24398298; DOI: 10.1016/j.bmcl.2013.12.066

実験手法

X-RAY DIFFRACTION (2 Å)