4NZ9
Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor
Summary for 4NZ9
Entry DOI | 10.2210/pdb4nz9/pdb |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADPH], 1-(4-methoxy-3-methylbenzyl)-5,6,7,8-tetrahydro-1H-naphtho[2,3-d]imidazole, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | rossman fold, reductase, nadph, reduction, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 2 |
Total formula weight | 63238.91 |
Authors | Mehboob, S.,Johnson, M.E.,Santarsiero, B.D. (deposition date: 2013-12-11, release date: 2014-12-31, Last modification date: 2023-09-20) |
Primary citation | Mehboob, S.,Truong, L.,Santarsiero, B.D.,Johnson, M.E. To be published To be Published, |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report