4NW9

Crystal structure of macrocycles containing Abeta17-23 (LVF(MEA)AED) and Abeta30-36 (AIIGL(ORN)V)

Summary for 4NW9

• Entry DOI: 10.2210/pdb4nw9/pdb
• Related: 4NTP 4NTR 4NW8
• Descriptor: Cyclic hexadecapeptide (ORN)LVF(MEA)AED(ORN)AIIGL(ORN)V, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
• Functional Keywords: beta-sheet, beta-hairpin, amyloid, de novo protein, protein binding
• Biological source: synthetic construct
• Total number of polymer chains: 12
• Total formula weight: 21309.89

Authors

Spencer, R.K.,Li, H.,Nowick, J.S. (deposition date: 2013-12-05, release date: 2014-04-02, Last modification date: 2023-09-20)

• Primary citation: Spencer, R.K.,Li, H.,Nowick, J.S.; X-ray crystallographic structures of trimers and higher-order oligomeric assemblies of a peptide derived from A beta (17-36).; J.Am.Chem.Soc., 136:5595-5598, 2014; PubMed: 24669800; DOI: 10.1021/ja5017409

Experimental method

X-RAY DIFFRACTION (1.66 Å)