4NW9
Crystal structure of macrocycles containing Abeta17-23 (LVF(MEA)AED) and Abeta30-36 (AIIGL(ORN)V)
Summary for 4NW9
Entry DOI | 10.2210/pdb4nw9/pdb |
Related | 4NTP 4NTR 4NW8 |
Descriptor | Cyclic hexadecapeptide (ORN)LVF(MEA)AED(ORN)AIIGL(ORN)V, CHLORIDE ION, SODIUM ION, ... (4 entities in total) |
Functional Keywords | beta-sheet, beta-hairpin, amyloid, de novo protein, protein binding |
Biological source | synthetic construct |
Total number of polymer chains | 12 |
Total formula weight | 21309.89 |
Authors | Spencer, R.K.,Li, H.,Nowick, J.S. (deposition date: 2013-12-05, release date: 2014-04-02, Last modification date: 2023-09-20) |
Primary citation | Spencer, R.K.,Li, H.,Nowick, J.S. X-ray crystallographic structures of trimers and higher-order oligomeric assemblies of a peptide derived from A beta (17-36). J.Am.Chem.Soc., 136:5595-5598, 2014 Cited by PubMed: 24669800DOI: 10.1021/ja5017409 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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