4NRU

Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative

4NRU の概要

• エントリーDOI: 10.2210/pdb4nru/pdb
• 分子名称: RNA dependent RNA polymerase, 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: rna dependent rna polymerase, murine norovirus, viral protein-transcription inhibitor complex, viral protein/transcription inhibitor
• 由来する生物種: Murine norovirus 1
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 354857.30

構造登録者

Milani, M.,Croci, R.,Pezzullo, M.,Tarantino, D.,Mastrangelo, E.,Bolognesi, M. (登録日: 2013-11-27, 公開日: 2014-10-15)

• 主引用文献: Croci, R.,Pezzullo, M.,Tarantino, D.,Milani, M.,Tsay, S.C.,Sureshbabu, R.,Tsai, Y.J.,Mastrangelo, E.,Rohayem, J.,Bolognesi, M.,Hwu, J.R.; Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.; Plos One, 9:e91765-e91765, 2014; PubMed: 24622391; DOI: 10.1371/journal.pone.0091765

実験手法

X-RAY DIFFRACTION (2.3 Å)