4NOD

Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

Summary for 4NOD

• Entry DOI: 10.2210/pdb4nod/pdb
• Descriptor: Transcription factor A, mitochondrial, 5'-D(*TP*TP*GP*GP*GP*GP*TP*AP*TP*GP*GP*GP*GP*CP*TP*TP*GP*GP*(BRU)P*TP*GP*G)-3', 5'-D(*CP*CP*AP*AP*CP*CP*AP*AP*GP*CP*CP*CP*CP*AP*TP*AP*CP*CP*CP*CP*AP*A)-3' (3 entities in total)
• Functional Keywords: hmg, dna bending, tfb2m, mtrnap, bru substitution to hsp1, t19, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Mitochondrion: Q00059
• Total number of polymer chains: 12
• Total formula weight: 162551.02

Authors

Ngo, H.B.,Lovely, G.A.,Phillips, R.,Chan, D.C. (deposition date: 2013-11-19, release date: 2014-01-22, Last modification date: 2023-09-20)

• Primary citation: Ngo, H.B.,Lovely, G.A.,Phillips, R.,Chan, D.C.; Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.; Nat Commun, 5:3077-3077, 2014; PubMed: 24435062; DOI: 10.1038/ncomms4077

Experimental method

X-RAY DIFFRACTION (2.897 Å)