4NFH
V207A Horse Liver Alcohol Dehydrogenase E complexed with NAD and 2,3,4,5,6-pentafluorobenzyl alcohol
Summary for 4NFH
Entry DOI | 10.2210/pdb4nfh/pdb |
Related | 3OQ6 4DWV 4NG5 |
Descriptor | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total) |
Functional Keywords | rossmann fold, dehyrogenase, nad, liver, cytosol, oxidoreductase |
Biological source | Equus caballus (domestic horse,equine) |
Cellular location | Cytoplasm: P00327 |
Total number of polymer chains | 2 |
Total formula weight | 82107.81 |
Authors | Plapp, B.V. (deposition date: 2013-10-31, release date: 2013-11-13, Last modification date: 2023-09-20) |
Primary citation | Yahashiri, A.,Rubach, J.K.,Plapp, B.V. Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis. Biochemistry, 53:881-894, 2014 Cited by PubMed: 24437493DOI: 10.1021/bi401583f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
Download full validation report