3OQ6

Horse liver alcohol dehydrogenase A317C mutant complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol

Summary for 3OQ6

• Entry DOI: 10.2210/pdb3oq6/pdb
• Related: 1hld
• Descriptor: Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
• Functional Keywords: rossmann fold, alcohol metabolism, nad, oxidoreductase
• Biological source: Equus caballus (domestic horse,equine)
• Cellular location: Cytoplasm: P00327
• Total number of polymer chains: 2
• Total formula weight: 82109.86

Authors

Plapp, B.V.,Herdendorf, T.J. (deposition date: 2010-09-02, release date: 2010-11-10, Last modification date: 2023-09-06)

• Primary citation: Herdendorf, T.J.,Plapp, B.V.; Origins of the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver A317C alcohol dehydrogenase.; Chem.Biol.Interact, 191:42-47, 2011; PubMed: 21184752; DOI: 10.1016/j.cbi.2010.12.015

Experimental method

X-RAY DIFFRACTION (1.2 Å)