3OQ6
Horse liver alcohol dehydrogenase A317C mutant complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alcohol dehydrogenase E chain | polymer | 374 | 39885.3 | 2 | UniProt (P00327) Pfam (PF08240) Pfam (PF00107) | Equus caballus (domestic horse equine) | |
| 2 | C, D, I, J (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, K (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) | non-polymer | 663.4 | 2 | Chemie (NAJ) | |||
| 4 | F, L (A, B) | 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL | non-polymer | 198.1 | 2 | Chemie (PFB) PubChem (9923) | |||
| 5 | G, H, M (A, B) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 3 | Chemie (MRD) PubChem (7870) PubChem (5288834) PubChem (5288845) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 1098 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 374 (UniProt: P00327)
| PDB | External Database | Details |
|---|---|---|
| Cys 317 | Ala 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79770.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2339.2 | |
| All* | Total formula weight | 82109.9 |
