4NB4

Pantothenamide-bound Pantothenate kinase from Staphylococcus aureus

Summary for 4NB4

• Entry DOI: 10.2210/pdb4nb4/pdb
• Related: 4NE2
• Descriptor: Type II pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, N-[2-(1,3-benzodioxol-5-yl)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... (5 entities in total)
• Functional Keywords: protein-substrate complex, transferase
• Biological source: Staphylococcus aureus
• Cellular location: Cytoplasm (Probable): Q6G7I0
• Total number of polymer chains: 8
• Total formula weight: 257801.66

Authors

Hughes, S.J.,Antoshchenko, T.,Smil, D.,Park, H.W. (deposition date: 2013-10-22, release date: 2014-03-05, Last modification date: 2023-09-20)

• Primary citation: Hughes, S.J.,Antoshchenko, T.,Kim, K.P.,Smil, D.,Park, H.W.; Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumoniae and Staphylococcus aureus.; Proteins, 82:1542-1548, 2014; PubMed: 24470271; DOI: 10.1002/prot.24524

Experimental method

X-RAY DIFFRACTION (2.25 Å)