4N84
Crystal structure of 14-3-3zeta in complex with a 12-carbon-linker cyclic peptide derived from ExoS
Summary for 4N84
Entry DOI | 10.2210/pdb4n84/pdb |
Related | 3CH8 3NKX 4IEA 4IHL 4N7G 4N7Y |
Descriptor | 14-3-3 protein zeta/delta, Exoenzyme S (3 entities in total) |
Functional Keywords | 14-3-3, adaptor protein, protein-protein interaction, cross-link, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P63104 |
Total number of polymer chains | 4 |
Total formula weight | 54748.01 |
Authors | Bier, D.,Glas, A.,Hahne, G.,Grossmann, T.,Ottmann, C. (deposition date: 2013-10-17, release date: 2014-02-19, Last modification date: 2014-03-12) |
Primary citation | Glas, A.,Bier, D.,Hahne, G.,Rademacher, C.,Ottmann, C.,Grossmann, T.N. Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53:2489-2493, 2014 Cited by PubMed: 24504455DOI: 10.1002/anie.201310082 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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