4N39
Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26)
Summary for 4N39
Entry DOI | 10.2210/pdb4n39/pdb |
Related | 4N3A 4N3B 4N3C |
Descriptor | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, Host cell factor 1, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | glycosyltransferase, o-glcnac transferase, proteolysis substrate, tpr domain, tpr binding, transferase-substrate complex, transferase/substrate |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform 2: Mitochondrion. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm: O15294 Cytoplasm: P51610 |
Total number of polymer chains | 2 |
Total formula weight | 82987.27 |
Authors | Lazarus, M.B.,Herr, W.,Walker, S. (deposition date: 2013-10-06, release date: 2014-01-01, Last modification date: 2024-02-28) |
Primary citation | Lazarus, M.B.,Jiang, J.,Kapuria, V.,Bhuiyan, T.,Janetzko, J.,Zandberg, W.F.,Vocadlo, D.J.,Herr, W.,Walker, S. HCF-1 is cleaved in the active site of O-GlcNAc transferase. Science, 342:1235-1239, 2013 Cited by PubMed: 24311690DOI: 10.1126/science.1243990 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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