4N19

Structural basis of conformational transitions in the active site and 80 s loop in the FK506 binding protein FKBP12

Summary for 4N19

DescriptorPeptidyl-prolyl cis-trans isomerase FKBP1A, SULFATE ION (3 entities in total)
Functional Keywordsisomerase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P62942
Total number of polymer chains1
Total molecular weight11968.62
Authors
Mustafi, S.M.,Brecher, M.B.,Zhang, J.,Li, H.M.,Lemaster, D.M.,Hernandez, G. (deposition date: 2013-10-03, release date: 2014-02-12, Last modification date: 2014-03-12)
Primary citation
Mustafi, S.M.,Brecher, M.,Zhang, J.,Li, H.,Lemaster, D.M.,Hernandez, G.
Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12.
Biochem.J., 458:525-536, 2014
PubMed: 24405377 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20131429
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.138301.1%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4n19
no rotation
Molmil generated image of 4n19
rotated about x axis by 90°
Molmil generated image of 4n19
rotated about y axis by 90°
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