4N0S
Complex of ERK2 with caffeic acid
Summary for 4N0S
Entry DOI | 10.2210/pdb4n0s/pdb |
Related | 3SA0 |
Descriptor | Mitogen-activated protein kinase 1, CAFFEIC ACID, SULFATE ION, ... (6 entities in total) |
Functional Keywords | caffeic acid complex, mitogen-activated protein kinase, signal-regulated kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, spindle : P28482 |
Total number of polymer chains | 1 |
Total formula weight | 42479.86 |
Authors | Kurinov, I.,Malakhova, M. (deposition date: 2013-10-02, release date: 2014-08-27, Last modification date: 2023-09-20) |
Primary citation | Yang, G.,Fu, Y.,Malakhova, M.,Kurinov, I.,Zhu, F.,Yao, K.,Li, H.,Chen, H.,Li, W.,Lim, D.Y.,Sheng, Y.,Bode, A.M.,Dong, Z.,Dong, Z. Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis. Cancer Prev Res (Phila), 7:1056-1066, 2014 Cited by PubMed: 25104643DOI: 10.1158/1940-6207.CAPR-14-0141 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7992 Å) |
Structure validation
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