4MWS

Crystal structure of human PPCA (trigonal crystal form 1)

4MWS の概要

• エントリーDOI: 10.2210/pdb4mws/pdb
• 関連するPDBエントリー: 1IVY 4MWT
• 分子名称: Lysosomal protective protein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: cathepsin a, glycoprotein, serine protease, carboxypeptidase, protective protein, n-linked glycosylation, proteolytically activated form, lysosomal enzyme, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99565.27

構造登録者

Kolli, N.,Garman, S.C. (登録日: 2013-09-25, 公開日: 2014-03-12, 最終更新日: 2023-09-20)

• 主引用文献: Kolli, N.,Garman, S.C.; Proteolytic activation of human cathepsin A.; J.Biol.Chem., 289:11592-11600, 2014; PubMed: 24599961; DOI: 10.1074/jbc.M113.524280

実験手法

X-RAY DIFFRACTION (2.8 Å)