4MVF

Crystal Structure of Plasmodium falciparum CDPK2 complexed with inhibitor staurosporine

Summary for 4MVF

• Entry DOI: 10.2210/pdb4mvf/pdb
• Descriptor: Calcium-dependent protein kinase 2, STAUROSPORINE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: ef-hands, protein s/t kinase, transferase-transferase inhibitor complex, calcium dependent protein kinase, calcium binding domain, transferase/transferase inhibitor
• Biological source: Plasmodium falciparum K1
• Total number of polymer chains: 1
• Total formula weight: 58805.92

Authors

Lauciello, L.,Pernot, L.,Scapozza, L.,Perozzo, R. (deposition date: 2013-09-24, release date: 2014-09-03, Last modification date: 2024-04-03)

• Primary citation: Lauciello, L.,Pernot, L.,Bottegoni, G.,Bisson, W.,Scapozza, L.,Perozzo, R.; P. falciparum Calcium-Dependent Protein Kinase 2 (PfCDPK2): First Crystal Structure and Virtual Ligand Screening; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)