4MVF
Crystal Structure of Plasmodium falciparum CDPK2 complexed with inhibitor staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium-dependent protein kinase 2 | polymer | 506 | 58127.1 | 1 | UniProt (O15865) | Plasmodium falciparum K1 | PfCDPK2 |
| 2 | B (A) | STAUROSPORINE | non-polymer | 466.5 | 1 | Chemie (STU) | |||
| 3 | C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G (A) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A: 30 - 511 (UniProt: O15865)
| PDB | External Database | Details |
|---|---|---|
| Met 14 | - | initiating methionine |
| Ala 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
| Thr 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Gln 21 | - | expression tag |
| Gln 22 | - | expression tag |
| Met 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Arg 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Asp 28 | - | expression tag |
| Pro 29 | - | expression tag |
| Leu 512 | - | expression tag |
| Glu 513 | - | expression tag |
| His 514 | - | expression tag |
| His 515 | - | expression tag |
| His 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58127.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 678.9 | |
| All* | Total formula weight | 58805.9 |
