4MVF
Crystal Structure of Plasmodium falciparum CDPK2 complexed with inhibitor staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium-dependent protein kinase 2 | polymer | 506 | 58127.1 | 1 | UniProt (O15865) | Plasmodium falciparum K1 | PfCDPK2 |
| 2 | B (A) | STAUROSPORINE | non-polymer | 466.5 | 1 | Chemie (STU) PubChem (71203703) PubChem (42610657) PubChem (44299148) PubChem (49831000) PubChem (68262703) PubChem (68306294) PubChem (73953205) PubChem (86306248) PubChem (122130844) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (358479) PubChem (5280487) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (12046017) PubChem (5279) PubChem (44259) PubChem (451705) PubChem (5459111) PubChem (6419748) PubChem (9804568) PubChem (9937179) | |||
| 3 | C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) PubChem (271) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | G (A) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A: 30 - 511 (UniProt: O15865)
| PDB | External Database | Details |
|---|---|---|
| Met 14 | - | initiating methionine |
| Ala 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
| Thr 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Gln 21 | - | expression tag |
| Gln 22 | - | expression tag |
| Met 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Arg 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Asp 28 | - | expression tag |
| Pro 29 | - | expression tag |
| Leu 512 | - | expression tag |
| Glu 513 | - | expression tag |
| His 514 | - | expression tag |
| His 515 | - | expression tag |
| His 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58127.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 678.9 | |
| All* | Total formula weight | 58805.9 |
