4MHX
Crystal Structure of Sulfamidase
Summary for 4MHX
Entry DOI | 10.2210/pdb4mhx/pdb |
Related | 4MIV |
Descriptor | N-sulphoglucosamine sulphohydrolase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | sulfatase fold, heparan, heparin, lysosome, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P51688 |
Total number of polymer chains | 2 |
Total formula weight | 118535.60 |
Authors | Sidhu, N.S.,Uson, I.,Schreiber, K.,Proepper, K.,Becker, S.,Gaertner, J.,Kraetzner, R.,Steinfeld, R.,Sheldrick, G.M. (deposition date: 2013-08-30, release date: 2014-05-14, Last modification date: 2021-06-02) |
Primary citation | Sidhu, N.S.,Schreiber, K.,Propper, K.,Becker, S.,Uson, I.,Sheldrick, G.M.,Gartner, J.,Kratzner, R.,Steinfeld, R. Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA. Acta Crystallogr.,Sect.D, 70:1321-1335, 2014 Cited by PubMed: 24816101DOI: 10.1107/S1399004714002739 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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