4MHX

Crystal Structure of Sulfamidase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	N-sulphoglucosamine sulphohydrolase	polymer	510	57912.2	2	UniProt (P51688) Pfam (PF00884) Pfam (PF16347)	Homo sapiens (human)	Sulfoglucosamine sulfamidase, Sulphamidase
2	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	G, J (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	H, I, K, L (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	M, N (B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	O, P (A, B)	water	water		18.0	205	Chemie (HOH)

Sequence modifications

A, B: 1 - 502 (UniProt: P51688)

PDB	External Database	Details
Fgp 70	Cys 70	modified residue
Arg 503	-	expression tag
Ser 504	-	expression tag
His 505	-	expression tag
His 506	-	expression tag
His 507	-	expression tag
His 508	-	expression tag
His 509	-	expression tag
His 510	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	115824.4
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1013.6
All*	Total formula weight	118535.6

*Water molecules are not included.