4MGY

Selective activation of Epac1 and Epac2

Summary for 4MGY

• Entry DOI: 10.2210/pdb4mgy/pdb
• Related: 2BYV 3CF6 4MGI 4MGK 4MGZ 4MH0
• Descriptor: Rap guanine nucleotide exchange factor 4, Ras-related protein Rap-1b, (2S,4aR,6R,7R,7aR)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9H-purin-9-yl}-7-methoxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-ol 2-oxide, ... (5 entities in total)
• Functional Keywords: guanine nucleotide exchange factor, nucleotide binding, signaling protein-gtp-binding protein complex, signaling protein/gtp-binding protein
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm: Q9EQZ6; Cell membrane: P61224
• Total number of polymer chains: 2
• Total formula weight: 98879.19

Authors

Rehmann, H. (deposition date: 2013-08-29, release date: 2014-09-03, Last modification date: 2023-09-20)

• Primary citation: Rehmann, H.; Selective activation of Epac1 and Epac2; To be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)