4MGJ

Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI

Summary for 4MGJ

Entry DOI	10.2210/pdb4mgj/pdb
Related	4MGL 4MGO
Descriptor	Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 4-(4-CHLOROPHENYL)IMIDAZOLE, ... (4 entities in total)
Functional Keywords	p450 fold, closed conformation, 4-cpi binding, oxidoreductase
Biological source	Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
Cellular location	Endoplasmic reticulum membrane; Peripheral membrane protein: P00178
Total number of polymer chains	1
Total formula weight	54965.19
Authors	Yang, Y.,Zhang, H.,Usharani, D.,Bu, W.,Im, S.,Tarasev, M.,Rwere, F.,Meagher, J.,Sun, C.,Stuckey, J.,Shaik, S.,Waskell, L. (deposition date: 2013-08-28, release date: 2014-08-13, Last modification date: 2024-02-28)
Primary citation	Yang, Y.,Zhang, H.,Usharani, D.,Bu, W.,Im, S.,Tarasev, M.,Rwere, F.,Pearl, N.M.,Meagher, J.,Sun, C.,Stuckey, J.,Shaik, S.,Waskell, L. Structural and Functional Characterization of a Cytochrome P450 2B4 F429H Mutant with an Axial Thiolate-Histidine Hydrogen Bond. Biochemistry, 53:5080-5091, 2014 Cited by PubMed: 25029089 DOI: 10.1021/bi5003794 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.41 Å)

Structure validation