4MEC

Crystal structure of RAT Heme oxygenase-1 in complex with ZN(II)-Protoporphyrin IX

Summary for 4MEC

• Entry DOI: 10.2210/pdb4mec/pdb
• Descriptor: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING ZN (2 entities in total)
• Functional Keywords: all alpha, oxygenase, heme binding, oxidoreductase
• Biological source: Rattus norvegicus (rat)
• Cellular location: Microsome: P06762
• Total number of polymer chains: 7
• Total formula weight: 192216.20

Authors

Sugishima, M. (deposition date: 2013-08-26, release date: 2014-08-27, Last modification date: 2023-11-08)

• Primary citation: Harada, E.,Sugishima, M.,Harada, J.,Fukuyama, K.,Sugase, K.; Distal regulation of heme binding of heme oxygenase-1 mediated by conformational fluctuations; Biochemistry, 54:340-348, 2015; PubMed: 25496210; DOI: 10.1021/bi5009694

Experimental method

X-RAY DIFFRACTION (3.2 Å)