4MDI

Immune Receptor

Summary for 4MDI

• Entry DOI: 10.2210/pdb4mdi/pdb
• Related: 4MCY 4MCZ 4MD0 4MD4 4MD5 4MDJ
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-4 beta chain, Citrullinated Vimentin, ... (7 entities in total)
• Functional Keywords: hla-dr, antigen presentation, t-cell receptor, citrullination, membrane, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 47488.67

Authors

Scally, S.W.,Rossjohn, J. (deposition date: 2013-08-22, release date: 2013-12-04, Last modification date: 2023-12-27)

• Primary citation: Scally, S.W.,Petersen, J.,Law, S.C.,Dudek, N.L.,Nel, H.J.,Loh, K.L.,Wijeyewickrema, L.C.,Eckle, S.B.,van Heemst, J.,Pike, R.N.,McCluskey, J.,Toes, R.E.,La Gruta, N.L.,Purcell, A.W.,Reid, H.H.,Thomas, R.,Rossjohn, J.; A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis.; J.Exp.Med., 210:2569-2582, 2013; PubMed: 24190431; DOI: 10.1084/jem.20131241

Experimental method

X-RAY DIFFRACTION (2 Å)