4MDI

Immune Receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class II histocompatibility antigen, DR alpha chain	polymer	189	21919.6	1	UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB	Homo sapiens (human)	MHC class II antigen DRA
2	B	HLA class II histocompatibility antigen, DRB1-4 beta chain	polymer	200	23253.6	1	UniProt (P13760) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB	Homo sapiens (human)	MHC class II antigen DRB1*4, DR-4, DR4
3	C	Citrullinated Vimentin	polymer	13	1386.6	1	UniProt (P08670) In PDB	Homo sapiens
4	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	B	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
7		water	water		18.0	397	Chemie (HOH)

Sequence modifications

A: 1 - 181 (UniProt: P01903)

PDB	External Database	Details
Thr 182	-	expression tag
Ser 183	-	expression tag
Gly 184	-	expression tag
Asp 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Lys 189	-	expression tag

B: 1 - 190 (UniProt: P13760)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Ile 67	Leu 96	variant
Asp 70	Gln 99	variant
Glu 71	Lys 100	variant
Val 86	Gly 115	variant
Thr 191	-	expression tag
Gly 192	-	expression tag
Gly 193	-	expression tag
Asp 194	-	expression tag
Asp 195	-	expression tag
Asp 196	-	expression tag
Asp 197	-	expression tag
Lys 198	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	46559.8
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	3
	Total formula weight	504.5
All*	Total formula weight	47488.7

*Water molecules are not included.