4MBF
Crystal structure of Penam sulfone PSR-4-157 bound to SHV-1 beta-lactamase
Summary for 4MBF
Entry DOI | 10.2210/pdb4mbf/pdb |
Related | 2H5S 4MBH 4MBK |
Descriptor | Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, 6-({(2R,3S)-3-carboxy-2-methyl-3-[(3-oxopropyl)amino]-2-sulfinopropyl}oxy)-6-oxohexanoic acid, ... (4 entities in total) |
Functional Keywords | class a beta-lactamase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 30687.02 |
Authors | |
Primary citation | Rodkey, E.A.,Winkler, M.L.,Bethel, C.R.,Pagadala, S.R.,Buynak, J.D.,Bonomo, R.A.,van den Akker, F. Penam sulfones and beta-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition. Plos One, 9:e85892-e85892, 2014 Cited by PubMed: 24454944DOI: 10.1371/journal.pone.0085892 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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