4MBH

Penam sulfone PSR-3-226 bound to E166A variant of SHV-1 beta-lactamase

Summary for 4MBH

Entry DOI	10.2210/pdb4mbh/pdb
Related	3RXW 4MBF 4MBK
Descriptor	Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, 3-(formylamino)-L-alanine, ... (5 entities in total)
Functional Keywords	class a beta-lactamase, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	30236.60
Authors	Rodkey, E.A.,van den Akker, F. (deposition date: 2013-08-19, release date: 2014-07-30, Last modification date: 2017-11-15)
Primary citation	Rodkey, E.A.,Winkler, M.L.,Bethel, C.R.,Pagadala, S.R.,Buynak, J.D.,Bonomo, R.A.,van den Akker, F. Penam sulfones and beta-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition. Plos One, 9:e85892-e85892, 2014 Cited by PubMed: 24454944 DOI: 10.1371/journal.pone.0085892 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.22 Å)

Structure validation