4M91

crystal structure of hN33/Tusc3-peptide 1

Summary for 4M91

• Entry DOI: 10.2210/pdb4m91/pdb
• Related: 4M8G 4M90 4M92
• Descriptor: Tumor suppressor candidate 3, Protein cereblon (3 entities in total)
• Functional Keywords: thioredoxin-like fold, formation of mixed disulfides, endoplasmic reticulum, oxidoreductase
• Biological source: Homo sapiens (human); More
• Cellular location: Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q13454; Cytoplasm : Q96SW2
• Total number of polymer chains: 2
• Total formula weight: 20620.56

Authors

Mohorko, E.,Owen, R.L.,Malojcic, G.,Brozzo, M.S.,Aebi, M.,Glockshuber, R. (deposition date: 2013-08-14, release date: 2014-03-26, Last modification date: 2023-09-20)

• Primary citation: Mohorko, E.,Owen, R.L.,Malojcic, G.,Brozzo, M.S.,Aebi, M.,Glockshuber, R.; Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.; Structure, 22:590-601, 2014; PubMed: 24685145; DOI: 10.1016/j.str.2014.02.013

Experimental method

X-RAY DIFFRACTION (1.1 Å)