4M71
Mutant structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-homocysteine and methylphenylpyruvic acid
Summary for 4M71
Entry DOI | 10.2210/pdb4m71/pdb |
Related | 4KIB 4KIC 4KIF 4KIG 4M6X 4M6Y 4M72 4M73 4M74 |
Descriptor | Methyltransferase MppJ, S-ADENOSYL-L-HOMOCYSTEINE, (3R)-2-oxo-3-phenylbutanoic acid, ... (8 entities in total) |
Functional Keywords | rossmann fold, methyltransferase, sam/ppy binding, transferase |
Biological source | Streptomyces hygroscopicus |
Total number of polymer chains | 2 |
Total formula weight | 76655.07 |
Authors | Liu, Y.C.,Zou, X.W.,Chan, H.C.,Huang, C.J.,Li, T.L. (deposition date: 2013-08-12, release date: 2014-06-25, Last modification date: 2023-11-15) |
Primary citation | Zou, X.W.,Liu, Y.C.,Hsu, N.S.,Huang, C.J.,Lyu, S.Y.,Chan, H.C.,Chang, C.Y.,Yeh, H.W.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L. Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70:1549-1560, 2014 Cited by PubMed: 24914966DOI: 10.1107/S1399004714005239 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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