4M71

Mutant structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-homocysteine and methylphenylpyruvic acid

4M71 の概要

• エントリーDOI: 10.2210/pdb4m71/pdb
• 関連するPDBエントリー: 4KIB 4KIC 4KIF 4KIG 4M6X 4M6Y 4M72 4M73 4M74
• 分子名称: Methyltransferase MppJ, S-ADENOSYL-L-HOMOCYSTEINE, (3R)-2-oxo-3-phenylbutanoic acid, ... (8 entities in total)
• 機能のキーワード: rossmann fold, methyltransferase, sam/ppy binding, transferase
• 由来する生物種: Streptomyces hygroscopicus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76655.07

構造登録者

Liu, Y.C.,Zou, X.W.,Chan, H.C.,Huang, C.J.,Li, T.L. (登録日: 2013-08-12, 公開日: 2014-06-25, 最終更新日: 2023-11-15)

• 主引用文献: Zou, X.W.,Liu, Y.C.,Hsu, N.S.,Huang, C.J.,Lyu, S.Y.,Chan, H.C.,Chang, C.Y.,Yeh, H.W.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L.; Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase; Acta Crystallogr.,Sect.D, 70:1549-1560, 2014; PubMed: 24914966; DOI: 10.1107/S1399004714005239

実験手法

X-RAY DIFFRACTION (2.21 Å)