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4M5X

Crystal structure of the USP7/HAUSP catalytic domain

Summary for 4M5X
Entry DOI10.2210/pdb4m5x/pdb
Related4M5W
DescriptorUbiquitin carboxyl-terminal hydrolase 7, BROMIDE ION (3 entities in total)
Functional Keywordsubiquitin-specific cysteine protease, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationNucleus : Q93009
Total number of polymer chains2
Total formula weight82536.66
Authors
Mesecar, A.D.,Molland, K.L.,Zhou, Q. (deposition date: 2013-08-08, release date: 2014-03-12, Last modification date: 2023-09-20)
Primary citationMolland, K.,Zhou, Q.,Mesecar, A.D.
A 2.2 angstrom resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding.
Acta Crystallogr F Struct Biol Commun, 70:283-287, 2014
Cited by
PubMed: 24598911
DOI: 10.1107/S2053230X14002519
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.187 Å)
Structure validation

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