4M5O
3-HYDROXY-6-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 H1N1 endonuclease
Summary for 4M5O
Entry DOI | 10.2210/pdb4m5o/pdb |
Related | 4LN7 4M5Q 4M5R 4M5U 4M5V 4MK1 4MK2 4MK5 |
Descriptor | Polymerase PA, MANGANESE (II) ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | cap-snatching, rna binding protein-inhibitor complex, rna binding protein/inhibitor |
Biological source | Influenza A virus (A/Lima/WRAIR1695P/2009(H1N1)) |
Total number of polymer chains | 1 |
Total formula weight | 29389.80 |
Authors | Bauman, J.D.,Patel, D.,Das, K.,Arnold, E. (deposition date: 2013-08-08, release date: 2013-09-18, Last modification date: 2024-02-28) |
Primary citation | Bauman, J.D.,Patel, D.,Baker, S.F.,Vijayan, R.S.,Xiang, A.,Parhi, A.K.,Martinez-Sobrido, L.,Lavoie, E.J.,Das, K.,Arnold, E. Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8:2501-2508, 2013 Cited by PubMed: 23978130DOI: 10.1021/cb400400j PDB entries with the same primary citation |
Experimental method |
Structure validation
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