4M2S
Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR
Summary for 4M2S
Entry DOI | 10.2210/pdb4m2s/pdb |
Related | 3G5U 3G60 3G61 4M1M 4M2T |
Descriptor | Multidrug resistance protein 1A, (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione (2 entities in total) |
Functional Keywords | atp-binding cassette transporter, multidrug efflux, adenosine triphosphate, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mus musculus (mouse) |
Cellular location | Cell membrane; Multi-pass membrane protein: P21447 |
Total number of polymer chains | 2 |
Total formula weight | 284730.20 |
Authors | Li, J.,Jaimes, K.F.,Aller, S.G. (deposition date: 2013-08-05, release date: 2013-11-13, Last modification date: 2024-02-28) |
Primary citation | Li, J.,Jaimes, K.F.,Aller, S.G. Refined structures of mouse P-glycoprotein. Protein Sci., 23:34-46, 2014 Cited by PubMed: 24155053DOI: 10.1002/pro.2387 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.4 Å) |
Structure validation
Download full validation report