4M0W
Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin
4M0W の概要
エントリーDOI | 10.2210/pdb4m0w/pdb |
分子名称 | Replicase polyprotein 1a, Ubiquitin, ZINC ION, ... (7 entities in total) |
機能のキーワード | papain-like protease-ubiquitin complex, protein hydrolase and deubiquitination, hydrolase-protein binding complex, hydrolase/protein binding |
由来する生物種 | SARS coronavirus (SARS-CoV) 詳細 |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8 Ubiquitin: Cytoplasm (By similarity): P62992 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 46214.76 |
構造登録者 | Chou, C.-Y.,Chen, H.-Y.,Lai, H.-Y.,Cheng, S.-C.,Chou, Y.-W. (登録日: 2013-08-02, 公開日: 2014-02-12, 最終更新日: 2023-11-08) |
主引用文献 | Chou, C.-Y.,Lai, H.-Y.,Chen, H.-Y.,Cheng, S.-C.,Cheng, K.-W.,Chou, Y.-W. Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease Acta Crystallogr.,Sect.D, 70:572-581, 2014 Cited by PubMed: 24531491DOI: 10.1107/S1399004713031040 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.4 Å) |
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