4M0U

crystal structure of human PRS1 Q133P mutant

Summary for 4M0U

• Entry DOI: 10.2210/pdb4m0u/pdb
• Related: 4LYG 4LZO 4LZP 4M0P
• Descriptor: Ribose-phosphate pyrophosphokinase 1, SULFATE ION (3 entities in total)
• Functional Keywords: prs1, prpp synthesis enzyme, atp r5p, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72222.97

Authors

Chen, P.,Teng, M.,Li, X. (deposition date: 2013-08-02, release date: 2015-02-04, Last modification date: 2023-11-08)

• Primary citation: Chen, P.,Liu, Z.,Wang, X.,Peng, J.,Sun, Q.,Li, J.,Wang, M.,Niu, L.,Zhang, Z.,Cai, G.,Teng, M.,Li, X.; Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations; Plos One, 10:e0120304-e0120304, 2015; PubMed: 25781187; DOI: 10.1371/journal.pone.0120304

Experimental method

X-RAY DIFFRACTION (2.74 Å)