4M0U
crystal structure of human PRS1 Q133P mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribose-phosphate pyrophosphokinase 1 | polymer | 326 | 35919.4 | 2 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I |
| 2 | C, D, E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 318 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Pro 133 | Gln 133 | engineered mutation |
| Leu 319 | - | expression tag |
| Glu 320 | - | expression tag |
| His 321 | - | expression tag |
| His 322 | - | expression tag |
| His 323 | - | expression tag |
| His 324 | - | expression tag |
| His 325 | - | expression tag |
| His 326 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71838.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 72223.0 |
