4LW7
Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
Summary for 4LW7
Entry DOI | 10.2210/pdb4lw7/pdb |
Related | 3LTP |
Descriptor | Orotidine 5'-phosphate decarboxylase, 6-HYDROXYURIDINE-5'-PHOSPHATE (3 entities in total) |
Functional Keywords | tim barrel fold, orotidine 5'-monophosphate decarboxylase, inhibitor bmp, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Methanothermobacter thermautotrophicus |
Total number of polymer chains | 2 |
Total formula weight | 50347.62 |
Authors | Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C. (deposition date: 2013-07-26, release date: 2014-07-30, Last modification date: 2023-09-20) |
Primary citation | Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP To be Published, |
Experimental method | X-RAY DIFFRACTION (1.423 Å) |
Structure validation
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