4LW7
Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Orotidine 5'-phosphate decarboxylase | polymer | 228 | 24833.6 | 2 | UniProt (O26232) Pfam (PF00215) In PDB | Methanothermobacter thermautotrophicus | OMP decarboxylase, OMPDCase, OMPdecase |
| 2 | A, B | 6-HYDROXYURIDINE-5'-PHOSPHATE | non-polymer | 340.2 | 2 | Chemie (BMP) | |||
| 3 | water | water | 18.0 | 469 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 228 (UniProt: O26232)
| PDB | External Database | Details |
|---|---|---|
| Pro 101 | Arg 101 | engineered mutation |
| Ser 128 | His 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49667.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 680.4 | |
| All* | Total formula weight | 50347.6 |
