4LRL

Structure of an Enterococcus Faecalis HD-domain protein complexed with dGTP and dTTP

4LRL の概要

• エントリーDOI: 10.2210/pdb4lrl/pdb
• 関連するPDBエントリー: 2O6I 3IRH
• 分子名称: HD domain protein, NICKEL (II) ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, hd domain, phosphohydrolase, dntpase, allosteric regulation, metal binding protein, hydrolase
• 由来する生物種: Enterococcus faecalis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 227342.39

構造登録者

Vorontsov, I.I.,Minasov, G.,Shuvalova, L.,Joachimiak, A.,Anderson, W.F.,Midwest Center for Structural Genomics (MCSG) (登録日: 2013-07-19, 公開日: 2013-11-20, 最終更新日: 2023-09-20)

• 主引用文献: Vorontsov, I.I.,Wu, Y.,Delucia, M.,Minasov, G.,Mehrens, J.,Shuvalova, L.,Anderson, W.F.,Ahn, J.; Mechanisms of Allosteric Activation and Inhibition of the Deoxyribonucleoside Triphosphate Triphosphohydrolase from Enterococcus faecalis.; J.Biol.Chem., 289:2815-2824, 2014; PubMed: 24338016; DOI: 10.1074/jbc.M113.524207

実験手法

X-RAY DIFFRACTION (2.35 Å)