4LJP

Structure of an active ligase (HOIP-H889A)/ubiquitin transfer complex

Summary for 4LJP

Entry DOI	10.2210/pdb4ljp/pdb
Related	4LJO 4LJQ
Descriptor	E3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION, ... (4 entities in total)
Functional Keywords	e3 ligase-ubiquitin complex, ligase, hoip, rnf31, ubiquitin, rbr ligase, e3 ligase, ring domain, ibr domain, zinc finger
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	33871.06
Authors	Rana, R.R.,Stieglitz, B.,Koliopoulos, M.G.,Morris-Davies, A.C.,Christodoulou, E.,Howell, S.,Brown, N.R.,Rittinger, K. (deposition date: 2013-07-05, release date: 2013-10-16, Last modification date: 2023-09-20)
Primary citation	Stieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Schaeffer, V.,Christodoulou, E.,Howell, S.,Brown, N.R.,Dikic, I.,Rittinger, K. Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature, 503:422-426, 2013 Cited by PubMed: 24141947 DOI: 10.1038/nature12638 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation