Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0071797 | cellular_component | LUBAC complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1101 |
| Chain | Residue |
| A | CYS871 |
| A | CYS874 |
| A | CYS890 |
| A | CYS893 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1102 |
| Chain | Residue |
| A | CYS898 |
| A | CYS901 |
| A | HIS926 |
| A | CYS930 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1103 |
| Chain | Residue |
| A | CYS916 |
| A | HIS923 |
| A | HIS925 |
| A | CYS911 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1104 |
| Chain | Residue |
| A | CYS969 |
| A | CYS986 |
| A | CYS998 |
| A | HIS1001 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CrHqFCsgCY |
| Chain | Residue | Details |
| A | CYS893-TYR902 | |
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Interacts with activating enzyme |
| Chain | Residue | Details |
| B | ARG54 | |
| B | ARG72 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Essential for function |
| Chain | Residue | Details |
| B | HIS68 | |
| Chain | Residue | Details |
| B | SER65 | |
| A | CYS874 | |
| A | CYS890 | |
| A | CYS893 | |
| A | CYS898 | |
| A | CYS901 | |
| A | CYS916 | |
| A | HIS925 | |
| Chain | Residue | Details |
| B | GLY76 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P62987 |
| Chain | Residue | Details |
| B | LYS6 | |
| B | LYS11 | |
| B | LYS27 | |
| B | LYS29 | |
| B | LYS33 | |
| B | LYS48 | |
| B | LYS63 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
| Chain | Residue | Details |
| B | GLY76 | |
