4LDL
Structure of beta2 adrenoceptor bound to hydroxybenzylisoproterenol and an engineered nanobody
Summary for 4LDL
Entry DOI | 10.2210/pdb4ldl/pdb |
Related | 4LDE 4LDO |
Descriptor | Lysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, 4-[(1R)-1-hydroxy-2-{[1-(4-hydroxyphenyl)-2-methylpropan-2-yl]amino}ethyl]benzene-1,2-diol, ... (6 entities in total) |
Functional Keywords | g protein coupled receptor, membrane protein-hydrolase complex, membrane protein/hydrolase |
Biological source | Enterobacteria phage T4 More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P07550 |
Total number of polymer chains | 2 |
Total formula weight | 67061.22 |
Authors | Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. (deposition date: 2013-06-24, release date: 2013-09-25, Last modification date: 2023-09-20) |
Primary citation | Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502:575-579, 2013 Cited by PubMed: 24056936DOI: 10.1038/nature12572 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
Download full validation report